Publicaciones del Período 2000-2009

Development and Validation of an HPLC Method for the Determination of Process-Related Impurities in Pridinol Mesylate, Employing Experimental Designs. Romina M. Bianchini, Patricia M. Castellano y Teodoro S. Kaufman. Anal. Chim. Acta 654, 141-147 (2009). Anal Chim Acta 2009 654 141.pdf (589432)
 
New Inhibitors of the Complement System Inspired in K76-COOH. A SAR Study of Filifolinol Derivatives Through Modifications of the C3’ Position. Enrique L. Larghi, María A. Operto, Rene Torres y Teodoro S. Kaufman. Bioorg. Med. Chem. Lett. 19, 6172-6175 (2009). Bioorg Med Chem Lett 2009 19 6172.pdf (454761)
 
Electrocyclization-Mediated Approach to 2-Methyltriclisine, an Unnatural Analog of the Azafluoranthene Alkaloid Triclisine. Claudio C. Silveira, Enrique L. Larghi, Samuel R. Mendes, Andrea B. J. Bracca, Francieli Rinaldi y Teodoro S. Kaufman. Eur. J. Org. Chem. 4637-4645 (2009). Eur J Org Chem 2009 4637.pdf (236467)
 
PCA-CR Analysis of Dissolution Profiles. A Chemometric Approach to Probe the Polymorphic Form of the Active Pharmaceutical Ingredient in a Drug Product. Rubén M. Maggio, Patricia M. Castellano y Teodoro S. Kaufman. Int. J. Pharm. 378, 187-193 (2009). Int J Pharm 2009 378 187.pdf (747085)
 
Aaptamine and Related Compounds. Their Isolation, Chemical Syntheses and Biological Activities. Enrique L. Larghi, María L. Bohn y Teodoro S. Kaufman. Tetrahedron 65, 4257-4282 (2009). Tetrahedron 2009 65 4257.pdf (1757382)
 
Monitoring of Fatty Acid Composition in Virgin Olive Oil by Fourier Transformed Infrared Spectroscopy coupled with Partial Least Squares. Rubén M. Maggio, Teodoro S. Kaufman, Michele Del Carlo, Lorenzo Cerretani, Alessandra Bendini, Angelo Cichelli y Dario Compagnone. Food Chem. 114, 1549-1554 (2009). Food Chem 2009 114 1549.pdf (371387)
 
Stress Studies on Pridinol Mesylate and Synthesis of Relevant Impurities. Development and Validation of an HPLC Method for Their Determination. Romina M. Bianchini, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal.. 48, 1151-1160 (2008). J Pharm Biomed Anal 2008 48 1151.pdf (1393767)
 
Synthesis of 2-Diphenylphosphinoyl-3,5-(diaryl)-3,4-dihydro-2H-thiopyrans by the Reaction of a Bis [(diphenylphosphinoyl)methyl)] Sulfide with  Chalcones. Claudio C. Silveira, Francieli Rinaldi, Mariana M. Bassaco y Teodoro S. Kaufman. Tetrahedron Lett. 49, 5782-5784 (2008). Tetrahedron Lett 2008 49 5782.pdf (293699)
 
A combined RCM-Bischler Napieralski Strategy Towards the Synthesis of the Carbon Skeleton of Excentricine and Related Stephaoxocanes. Enrique L. Larghi y Teodoro S. Kaufman. Tetrahedron 64, 9921-9927 (2008). Tetrahedron 2008 64 9921.pdf (446542)
 
A Formal Total Synthesis of the Marine Alkaloid Aaptamine. Enrique L. Larghi, Blaise V. Obrist y Teodoro S. Kaufman. Tetrahedron 64, 5236-5245 (2008). Tetrahedron 2008 64 5236.pdf (535019)
 
A Multivariate Approach for the Simultaneous Determination of Losartan Potassium and Hydrochlorothiazide in a Combined Pharmaceutical Tablet Formulation. Rubén M. Maggio, Patricia M. Castellano y Teodoro S. Kaufman. Anal. Bioanal. Chem. 391, 2949-2955 (2008). Anal Bioanal Chem 2008 391 2949.pdf (153908)
 
A New Principal Component Analysis-Based Approach for testing ‘similarity’ of Drug Dissolution Profiles. Rubén M. Maggio, Patricia M. Castellano y Teodoro S. Kaufman. Eur. J. Pharm. Sci. 34, 66-77 (2008). Eur J Pharm Sci 2008 34 66.pdf (1131197)
 
An Alternative and Convenient synthesis of Oct-7-enal, a Naturally-Occurring Aldehyde Isolated From the Japanese Thistle Cirsium dipsacolepis. Andrea B. J. Bracca y Teodoro S. Kaufman. J. Braz. Chem. Soc. 19, 1125-1128 (2008). J Braz Chem Soc 2008 19 1125.pdf (133562)
 
Method Development and Validation for the Simultaneous Determination of Meloxicam and Pridinol Mesylate Using RP-HPLC and Application in Drug Formulations. Silvana E. Vignaduzzo, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 46, 219-225 (2008). J Pharm Biomed Anal 2008 46 219.pdf (444157)
 
Evaluación y Análisis de Parámetros de Calidad de Comprimidos de Paracetamol. María A. Operto, Patricia M. Castellano y Teodoro S. Kaufman. Latin Am. J. Pharm. 27, 603-607 (2008). Latin Am J Pharm 2008 27 603.pdf (112399)
 
Synthesis of the Carbon Framework of the Stephaoxocanes Employing a Sequential RCM/Pomeranz-Fritsch Approach. Andrea B. J. Bracca y Teodoro S. Kaufman. Eur. J. Org. Chem. 5284-5293 (2007). Eur J Org Chem 2007 5284.PDF (187,6 kB) 
 
Alternative and Improved Method for the Simultaneous Determination of Fexofenadine and Pseudoephedrine in their Combined Tablet Formulation, Rubén M. Maggio, Patricia M. Castellano, Silvana E. Vignaduzzo y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 45, 804-810 (2007). J Pharm Biomed Anal 2007 45 804.pdf (212799)
 
Thiophenol-Mediated Improvement of the Pictet-Spengler Cyclization of N-tosyl-beta-phenethylamines with Aldehydes. Claudio C. Silveira, Adriano S. Vieira y Teodoro S. Kaufman. Tetrahedron Lett. 47, 7545-7549 (2006). Tetrahedron Lett 2006 47 7545.pdf (203022)
 
Synthesis and Complement Inhibitory Activity of 3H-Spiro[benzofuran-2,1’-cyclohexanes] Derived from the Naturally-Occurring Filifolinol. Mariana Useglio, Patricia M. Castellano, María A. Operto, René Torres y Teodoro S. Kaufman. Bioorg. Med. Chem. Lett. 16, 5097-5101 (2006). Bioorg Med Chem Lett 2006 16 5097.pdf (153213)
 
Polysubstituted Isochroman Derivatives with Plant Growth Regulating Properties on Wheat (Triticum aestivum L.). Darío A. Bianchi, Luciano Brambilla, Martha A. Gattuso y Teodoro S. Kaufman. J. Plant Growth Regul. 25, 332-338 (2006). J Plant Growth Regul 2006 25 332.pdf (186992)
 
Synthesis and Antimicrobial Activity of Isochroman-quinones Related to the Pyranonaphthoquinone Antibiotics. Sebastián H. Lagorio, Darío A. Bianchi, Emma G. Sutich y Teodoro S. Kaufman. Eur. J. Med. Chem. 41, 1333-1338 (2006). Eur J Med Chem 2006 41 1333.pdf (286220)
 
Synthesis of N-Methyl-N-formyltyramine, a New beta-phenethylamide Derivative Isolated from Cyathobasis fruticulosa (Bunge) Aellen. Enrique L. Larghi y Teodoro S. Kaufman. J. Braz. Chem. Soc. 17, 599-602 (2006). J Braz Chem Soc 2006 17 599.pdf (135179)
 
The Oxa-Pictet-Spengler Cyclization. Synthesis of Isochromanes and Related Pyran-Type Heterocycles. Enrique L. Larghi y Teodoro S. Kaufman. Synthesis 187-210 (2006). Synthesis 2006 187.pdf (625164)
 
An Economical and Convenient Carbonyl Transposition Approach Towards a 2-Arylcycloheptanone Derivative. Andrea B. J. Bracca y Teodoro S. Kaufman. Synth. Commun. 36, 299-310 (2006). Synth Commun 2006 36 299.pdf (197929)
 
PLS and first derivative of ratio spectra mehtods for determination of hydrochlorothiazide and propranolol hydrochloride in tablets. Silvana E. Vignaduzzo, Rubén M. Maggio, Patricia M. Castellano y Teodoro S. Kaufman. Anal. Bioanal. Chem. 386, 2239-2244 (2006). Anal Bioanal Chem 2006 386 2239.pdf (205944)
 
1-Substituted beta-Carbolines by a Pictet-Spengler Cyclization with Thioorthoesters and Carbon-Carbon Bond Formation via N-Sulfonyl Iminium Ions Generated From N,S-Sulfonyl Acetals. Claudio C. Silveira, Luciana Félix, Antonio L. Braga y Teodoro S. Kaufman. Org. Lett.  7, 3701-3704 (2005). Organic Letters 2005 7 3701.pdf (73034)
 
The Intermolecular Pictet-Spengler Condensation with Chiral Carbonyl Derivatives in the Stereoselective Syntheses of Optically-Active Isoquinoline and Indole Alkaloids. Enrique L. Larghi, Marcela Amongero, Andrea B. J. Bracca y Teodoro S. Kaufman. ARKIVOC xii, 98-153 (2005). Arkivoc 2005 xii 98.pdf (993511)
 
Application of a Chemometric Method for the Simultaneous Determination of Acetaminophen and diclofenac in content-uniformity and drug –dissolution studies. Silvana E. Vignaduzzo, Patricia M. Castellano, Rubén M. Maggio y Teodoro S. Kaufman. Anal. Bioanal. Chem. 382, 1711-1714 (2005). Anal Bioanal Chem 2005 382 1711.pdf (225063)
 
Synthesis of Tricyclic Analogs of Stephaoxocanidine and Their Evaluation as Acetylcholinesterase Inhibitors. Darío A. Bianchi, Andrea B. J. Bracca, Guillermo Schmeda Hirschmann, Cristina Theoduloz y Teodoro S. Kaufman. Bioorg. Med. Chem. Lett. 15, 2711-2715 (2005). Bioorg Med Chem Lett 2005 15 2711.pdf (185505)
 
Approaches to the Total Synthesis of Calycotomine, a Widespread 1-Hydroxymethyl-Substituted Simple Tetrahydroisoquinoline. Teodoro S. Kaufman. Synthesis 339-360 (2005). Synthesis 2005 339.pdf (1769370)
 
The Quest for Quinine. Those Who Won the Battles and Those Who Won the War. Edmundo A. Rúveda y Teodoro S. Kaufman. Angew. Chem., Int. Ed. Eng. 44, 854-885 (2005). Angew Chem 2005 44 854.pdf (1013805)
 
Synthetic Approaches to Carnegine, a Simple Tetrahydroisoquinoline. Andrea B. J. Bracca y Teodoro S. Kaufman. Tetrahedron 60, 10575-10610 (2004). Tetrahedron 2004 60 10575.pdf (2315216)
 
Synthetic Approaches to 2-Tetralones. Claudio C. Silveira, Antonio L. Braga, Teodoro S. Kaufman y Eder J. Lenardão. Tetrahedron 60, 8295-8328 (2004). Tetrahedron 2004 60 8295.pdf (2935809)
 
On Robert B. Woodward and the Total Synthesis of Quinine. Teodoro S. Kaufman y Edmundo A. Rúveda; Comentario sobre Kauffman, G. B. Chem. Educator 9, 172-176 (2004), Robert B. Woodward: Organic Synthesizer par Excellence. On the 25th Anniversary of His Death. Chemical Educator [Online], https://chemeducator.org. Chem Educator 2004 19 07.pdf (183256)
 
Synthetic Pathways to Salsolidine. Teodoro S. Kaufman. Tetrahedron:Asymmetry 15, 1203-1237 (2004). Tetrahedron Asymmetry 2004 15 1205.pdf (676976)
 
New and Improved Synthesis of (+/-)-4-Bromo-7,8-dimethoxy-isochroman-3-one, a Key Intermediate for the Elaboration of (+/-)-cis-Alpinine and (+/-)-cis-Alpinigenine. Darío A. Bianchi y Teodoro S. Kaufman. Org. Prep. Proc. Int. 36, 195-199 (2004). Org Prep Proc Int 2004 32 195.pdf (2146641)
 
Synthesis and Plant Growth Regulating Properties of 4-Hydroxy-7,8-dimethoxy-isochroman-3-one on Tobacco (Nicotiana tabacum cv Petit Havana). Darío A. Bianchi, Néstor J. Carrillo, Nicolás E. Blanco y Teodoro S. Kaufman. J. Agric. Food Chem. 52, 1923-1927 (2004). J Agric Food Chem 2004 52 1923.pdf (149530)
 
Studies on the Intramolecular Oxa-Pictet-Spengler Rearrangement of 5-Aryl-1,3-Dioxolanes to 4-Hydroxy-Isochromans. Darío A. Bianchi, Federico Rúa y Teodoro S. Kaufman. Tetrahedron Lett. 45, 411-415 (2004). Tetrahedron Lett 2004 45 411.pdf (281509)
 
A Concise Strategy Towards the Isochroman-gamma-Lactone Unit of the Naphthoquinone Antineoplasic Antibiotics. Darío A. Bianchi, Emma G. Sutich y Teodoro S. Kaufman. Bioorg. Med.Chem.Lett. 14, 757-760 (2004). Bioorg Med Chem Lett 2004 14 757.pdf (175139)
 
Chemometric Determination of Amiloride Hydrochloride, Atenolol, Hydrochlorothiazide and Timolol Maleate in Synthetic Mixtures and Pharmaceutical Formulations. Mónica C. F. Ferraro, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 34, 305-314 (2004). J Pharm Biomed Anal 2004 34 305.pdf (104386)
 
Model Studies Towards Stephaoxocanes: Construction of the 2-Oxa-4-azaphenalene Core of Stephaoxocanidine and Eletefine. Darío A. Bianchi, Marcos A. Cipulli y Teodoro S. Kaufman. Eur. J. Org. Chem. 4731-4736 (2003). Eur J Org Chem 2003 4731.pdf (143001)
 
Chemometrics-Assisted Simultaneous Determination of Atenolol and Chlorthalidone in Synthetic Binary Mixtures and Pharmaceutical Dosage Forms. Mónica C. F. Ferraro, Patricia M. Castellano y Teodoro S. Kaufman. Anal. Bioanal. Chem. 377, 1159-1164 (2003). Anal Bioanal Chem 2003 377 1159.pdf (213374)
 
Synthesis and Complement Inhibitory Activity of B/C/D/-Ring Analogues of the Fungal Metabolite 6,7-Diformyl-3’,4’,4a’,5’,6’,7’,8’,8a’- octahydro-4,6’,7’- trihydroxy-2’,5’,8a’- tetramethylspiro [1’(2’H)- naphtha-lene-2(3H)-benzofuran]. Barton J. Bradbury, Piotr Bartyzel, Teodoro S. Kaufman, Marcelo J. Nieto, Robert D. Sindelar, Susanne M. Scesney, Bruce R. Gaumond y Henry C. Marsh Jr. J. Med. Chem. 46, 2697-2705 (2003). J Med Chem 2003 46 2697.pdf (149344)
 
Synthesis of a Tricyclic Lactone Embodying the ABC-Ring System of Stephaoxocanidine, by Tin(IV) Chloride-Assisted Sulfonamidoacetal Cyclization and an Aromatization Promoted by Triethylamine. Darío A. Bianchi y Teodoro S. Kaufman. ARKIVOC x, 178-188 (2003). Arkivoc 2003 x 178.pdf (61897)
 
Thioorthoesters in the Activated Pictet-Spengler Cyclization. Synthesis of 1-Thiosubstituted Tetrahydroisoquinolines and Carbon-Carbon Bond Formation via Sulfonyl Iminium Ions Generated from N,S-Sulfonyl Acetals. Claudio C. Silveira, Carmem R. Bernardi, Antonio L. Braga y Teodoro S. Kaufman. Tetrahedron Lett. 44, 6137-6140 (2003). Tetrahedron Lett 2003 44 6137.pdf (122284)
 
Simultaneous Determination of Amiloride Hydrochloride and Hydrochlorothiazide in Synthetic Samples and Pharmaceutical Formulations by Multivariate Analysis of Spectrophotometric Data. Mónica C. F. Ferraro, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 30, 1121-1131 (2002). J Pharm Biomed Anal 2002 30 1121.pdf (170669)
 
A Simple Protocol for the One Pot Synthesis of Chiral Secondary Benzylic Alcohols by Catalytic Enantioselective Reduction of Aromatic Ketones. Viviana L. Ponzo y Teodoro S. Kaufman. Synlett 1128-1130 (2002). Synlett 2002 1128.pdf (40879)
 
Desulfonylation of N-Sulfonyl Tetrahydroisoquinoline Derivatives by Potassium Fluoride on Alumina Under Microwave Irradiation. Selective Synthesis of 3,4-Dihydroisoquinolines and Isoquinolines. Claudio C. Silveira, Carmem R. Bernardi, Antonio L. Braga y Teodoro S. Kaufman. Synlett 906-910 (2002). Synlett 2002 907.pdf (62652)
 
Elaboration of 1-Benzoyltetrahydroisoquinoline Derivatives Employing a Pictet-Spengler Cyclisation with -Chloro--Phenylthio Ketones. Synthesis of O-Methylvelucryptine. Claudio C. Silveira, Carmem R. Bernardi, Antonio L. Braga y Teodoro S. Kaufman. Tetrahedron Lett. 42, 8947-8950 (2001). Tetrahedron Lett 2001 42 8947.pdf (95904)
 
A Spectrophotometric-Partial Least Squares (PLS-1) Method for the Simultaneous Determination of Furosemide and Amiloride Hydrochloride in Pharmaceutical Formulations. Mónica C. F. Ferraro, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 26, 443-451 (2001). J Pharm Biomed Anal 2001 26 443.pdf (118323)
 
Sulfonamidoacetal Cyclization-Based Synthesis of a Tetrahydrooxazaphenalene Lactone Related to the ABC-Ring System of the Stephaoxocanes. Teodoro S. Kaufman. Heterocycles 55, 323-330 (2001). Heterocycles 2001 55 323.pdf (253895)
 
A Tosyliminium-ion Based Total Synthesis of Schefferine. Darío A. Bianchi y Teodoro S. Kaufman. Can. J. Chem. 78, 1165-1169 (2000). Can J Chem 2000 78 1165.pdf (72242)
 
Electrophilic Aromatic Substitution by Use of N-Tosyliminium Ions. Elaboration of 3-Substituted Tetrahydro-isoquinolines. Darío A. Bianchi y Teodoro S. Kaufman, Synlett 801-804 (2000). Synlett 2000 801.pdf (71703)
 
Synthetic Studies on Natural Stephaoxocanes. Elaboration of a Tetrahydrooxazaphenalene Potential Intermediate. Teodoro S. Kaufman. Molecules 5, 491-492 (2000). Molecules 2000 5 491.pdf (19038)
 
Elaboration of the Isochromane System of Stephaoxocanes Employing an Oxa-Pictet Spengler Type Cyclization. Teodoro S. Kaufman, Carmem R. Bernardi, Marcos Cipulli y Claudio C. Silveira. Molecules 5, 493-494 (2000). Molecules 2000 5 493.pdf (19276)
 
Practical and Efficient Procedure for the In Situ Preparation of B-Alkoxyoxazaborolidines. Enantioselective Reduction of Prochiral Ketones. Viviana L. Ponzo y Teodoro S. Kaufman. Molecules 5, 495-496 (2000). Molecules 2000 5 495.pdf (15137)