Thermally Induced Solid-State Transformation of Cimetidine. A Multi-spectroscopic/Chemometrics Determination of the Kinetics of the Process and Structural Elucidation of one of the Products as a Stable N3-Enamino Tautomer. Natalia L. Calvo, Sebastian O. Simonetti, Rubén M. Maggio, Teodoro S. Kaufman. Anal. Chim. Acta 875, 22-32 (2015). Anal Chim Acta 2015 875 22.pdf (1691724)

Metal-free Synthesis of 3,5-Disubstituted 1H- and 1-aryl-1H-pyrazoles from 1,3-Diyne-indole Derivatives Employing Two Successive Hydroaminations. Mariana M. Bassaco, Margiani P. Fortes, Teodoro S. Kaufman y Claudio C. Silveira. RSC Adv. 5, 21112-21124 (2015). RSC Adv 2015 5 21112.pdf (345103) 

Alternate and Step-Economic Synthesis of the b-Methylstyrene Chelating Pre-ligand of the Hoveyda-Grubbs’ II Catalyst. Sebastian O. Simonetti, Enrique L. Larghi y Teodoro S. Kaufman. Org. Prep. Proced. Int. 47, 227-231 (2015). Org Prep Proc Int 2015 47 227.pdf (160829)

A PCA-Based Chemometrics-Assisted ATR-FTIR Approach for the Classification of Polymorphs of Cimetidine. Application to Physical Mixtures and Tablets. Natalia L. Calvo, Rubén M. Maggio y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 107, 419-425 (2015). J Pharm Biomed Anal 2015 107 419.pdf (1029664) 

An Eco-friendly Synthesis of Novel 3,5-Disubstituted-1,2-isoxazoles in PEG-400, Employing the Et3N-Promoted Hydroamination of Symmetric and Unsymmetric 1,3-Diyne-indole Derivatives. Mariana M. Bassaco, Margiani P. Fortes, Davi F. Back, Teodoro S. Kaufman y Claudio C. Silveira. RSC Adv. 4, 60785–60797 (2014).  RSC Advances 2014 4 60785.pdf (384405)
 
Neocryptolepine (Cryprotackieine). A Unique Bioactive Natural Product: Isolation, Synthesis and Profile of its Biological Activity. Andrea B. J. Bracca, Enrique L. Larghi, Daniel A. Heredia y Teodoro S. Kaufman. Eur. J. Org. Chem. 7979–8003 (2014). Eur J Org Chem 2014 7979.pdf (3599460)
 
A Convenient Eco-Friendly System for the Synthesis of 5-Sulfenyl Tetrazole Derivatives of Indoles and Pyrroles Employing CeCl3.7H2O in PEG-400. Margiani P. Fortes, Mariana M. Bassaco, Teodoro S. Kaufman y Claudio C. Silveira. RSC Adv. 4, 34519-34530 (2014). RSC Adv 2014 4 34519.pdf (342412)
 
Synthesis and Photophysical Characterization of Novel p-Conjugated Vinyl Sulfides. Mariana M. Bassaco, Matias Monçalves, Francieli Rinaldi, Teodoro S. Kaufman y Claudio C. Silveira. J. Photochem. Photobiol. A: Chem. 290, 1-10 (2014). J Photochem Photobiol A 2014 290 1.pdf (1786601)
 
Synthesis and Evaluation of Symmetrically Substituted 3,3-Dibenzyl-4-hydroxy-3,4-dihydro-1H-quinolin-2-ones. A Novel Family of Quinoline Derivatives with Interesting Antibacterial Activity. Matías D. Ferretti, Alexandre T. Neto, Ademir F. Morel, Teodoro S. Kaufman y Enrique L. Larghi. Eur. J. Med. Chem. 81, 253-266 (2014). Eur J Med Chem 2014 81 253.pdf (1014253)
 
Facile and Convenient Sequential Homobimetallic Catalytic Approach Towards b-Methylstyrenes. A One-pot Stille Cross-coupling/Isomerization Strategy. Sebastian O. Simonetti, Enrique L. Larghi y Teodoro S. Kaufman. Org. Biomol. Chem. 12, 3735-3743 (2014). Org Biomol Chem 2014 12 3735.pdf (192323)
 
Pharmaceutical Impurities and Degradation Products: Uses and Applications of NMR Techniques. Rubén M. Maggio, Natalia L. Calvo, Silvana E. Vignaduzzo y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 101, 102-122 (2014). J Pharm Biomed Anal 2014 101 102.pdf (2664671)
 
Modulators of Complement Activation: A Patent Review (2008 - 2013). Enrique L. Larghi y Teodoro S. Kaufman. Exp. Opin. Ther. Pat. 12, 665-686 (2014). Exp Opin Ther Pat 2014 24 665.pdf (1170566)
 
Facile, Efficient and Eco-Friendly Synthesis of 5-Sulfenyl Tetrazole Derivatives of Indoles and Pyrroles. Bruna L. Kuhn, Margiani P. Fortes, Teodoro S. Kaufman y Claudio C. Silveira. Tetrahedron Lett. 55, 1648-1652 (2014).  Tetrahedron Lett 2014 55 1648.pdf (722437)
 
A Dynamic Thermal ATR-FTIR/Chemometrics Approach to the Analysis of Polymorphic Interconversions. Cimetidine as a Model Drug”, Natalia L. Calvo, Rubén M. Maggio y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 92, 90-97 (2014). J Pharm Biomed Anal 2014 92 90.pdf (1129529)
 
An Eco-Friendly Strategy, using On-Line Monitoring and Dilution Coupled to a Second-Order Chemometric Method, for the Construction of Dissolution Curves of Combined Pharmaceutical Associations”. Natalia L. Calvo, Rubén M. Maggio y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 89, 213-220 (2014).  J Pharm Biomed Anal 2014 89 213.pdf (986591)
 
Modular CeCl3.7H2O-Catalysed Multi-component Synthesis of 1,2,3,4-Tetrasubstituted Pyrroles Under Microwave Irradiation and their Further Trichloroisocyanuric Acid-Mediated Conversion into 5-Sulfenylpyrrole Derivatives. Claudio C. Silveira, Samuel R. Mendes, Guilherme M. Martins, Sheila C. Schlösser y Teodoro S. Kaufman. Tetrahedron 69, 9076-9085 (2013). Tetrahedron 2013 69 9076.pdf (2298904)
 
Angular Tricyclic Benzofurans and Related Natural Products of Fungal Origin. Isolation, Biological Activity and Synthesis. Sebastián O. Simonetti, Enrique L. Larghi, Andrea B. J. Bracca y Teodoro S. Kaufman. Nat. Prod. Rep. 30, 941-969 (2013).  Nat Prod Rep 2013 30 941.pdf (923812)
 
Stability-indicating Methods for the Assay of Bulk Drugs and Drug Formulations. A Regulatory Perspective. Rubén M. Maggio, Silvana E. Vignaduzzo y Teodoro S. Kaufman. Trends in Anal. Chem. 49, 57-70 (2013). Trends Anal Chem 2013 49 57.pdf (1352631)
 
A Multivariate Curve Resolution Approach to the Study of the Degradation Kinetics of Valsartan Under Photolytic and Acid Conditions. Romina M. Bianchini and Teodoro S. Kaufman. Int. J. Chem. Kinet. 45, 734-743 (2013).  Int J Chem Kinet 2013 45 734.pdf (863912)
 
Development and Validation of an HPLC Method for the Simultaneous Determination of Bromhexine, Chlorpheniramine, Paracetamol and Pseudoephedrine in their Combined Cold Medicine Formulations. Silvana E. Vignaduzzo y Teodoro S. Kaufman. J. Liq. Chromatogr. Relat. Technol. 36, 2829-2843 (2013). J Liq Chromatogr Relat Technol 2013 36 2829.pdf (516341)
 
Simultaneous Acquisition of the Dissolution Curves of Two Active Ingredients in a Binary Pharmaceutical Association, Employing an On-line Circulation System and Chemometrics-Assistance. Rubén M. Maggio, María A. Rivero y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 72, 51-58 (2013). J Pharm Biomed Anal 2013 72 51.pdf (706472)
 
Synthesis of Optically Active 1,2,3-Trisubstituted Azetidines Employing an Organocatalytic Approach with L-Proline. Marcela Amongero y Teodoro S. Kaufman. Tetrahedron Lett. 54, 1924-1927 (2013). Tetrahedron Lett 2013 54 1924.pdf (424607)
 
CeIII-Promoted Oxidation. Efficient Aerobic One-pot Eco-friendly Synthesis of Oxidized Bis(indol-3-yl)methanes and Cyclic Tetra(indolyl)dimethanes. Claudio C. Silveira, Samuel R. Mendes, Marcos A. Villetti, Davi F. Back y Teodoro S. Kaufman. Green Chem. 14, 2912-2921 (2012). Green Chem 2012 14 2912.pdf (852988)
 
Synthesis and Classical Pathway Complement Inhibitory Activity of C7-Functionalized Filifolinol Derivatives, Inspired in K-76 COOH. Enrique L. Larghi, María A. Operto, René Torres y Teodoro S. Kaufman. Eur. J. Med. Chem. 55, 74-84 (2012).  Eur J Med Chem 2012 55 74.pdf (488043)
 
Synthesis of the Unique Angular Tricyclic Chromone Structure Proposed for Aspergillitine, and its Relationship with Alkaloid TMC-120B. Sebastian O. Simonetti, Enrique L. Larghi, Andrea B. J. Bracca y Teodoro S. Kaufman. Org. Biomol. Chem. 10, 4124-4134 (2012).  Org Biomol Chem 2012 10 4124.pdf (249623)
 
Stress Testing of Valsartan. Development and Validation of a High Performance Liquid Chromatography Stability-Indicating Assay. Romina M. Bianchini, Patricia M. Castellano y Teodoro S. Kaufman. J. Liq. Chromatogr. Relat. Technol. 35, 1053-1069 (2012). J Liq Chromatogr Relat Technol 2012 35 1053.pdf (705722)
 
Multivariate Optimization and Validation of a CZE Method for the Analysis of Pridinol Mesylate and Meloxicam in Tablets. Silvana E. Vignaduzzo, Luciana Vera-Candioti, Patricia M. Castellano, Héctor C. Goicoechea y Teodoro S. Kaufman. Chromatographia 74, 609-617 (2011). Chromatographia 2011 609.pdf (1772625)
 
Development and Validation of an HPLC Method for the Simultaneous Determination of Amlodipine, Hydrochlorothiazide and Valsartan in Tablets of Their Novel Triple Combination and Binary Pharmaceutical Associations. Silvana E. Vignaduzzo, Patricia M. Castellano y Teodoro S. Kaufman. J. Liq. Chromatogr. Relat. Technol. 34, 2383-2395 (2011). J Liq Chromatogr Relat Technol 2011 34 2383.pdf (621426)
 
Synthesis of Oxacycles Employing the Oxa-Pictet-Spengler Reaction. Recent Developments and New Prospects. Enrique L. Larghi y Teodoro S. Kaufman. Eur. J. Org. Chem. 5195-5231 (2011). Eur J Org Chem 2011 5195.pdf (2167427)
 
Characterization of Two New Potential Impurities of Valsartan Obtained Under Photodegradation Stress Condition. Romina M. Bianchini, Patricia M. Castellano y Teodoro S. Kaufman. J. Pharm. Biomed. Anal. 56,  16-22 (2011). J Pharm Biomed Anal 2011 56 16.pdf (684713)
 
Synthesis of (Diphenylphosphinoyl)methyl Vinyl Sulfides, Symmetric and Unsymmetric Divinyl Sulfides Employing Bis[(diphenylphosphinoyl)methyl] Sulfide. Claudio C. Silveira, Francieli Rinaldi, Mariana M. Bassaco, Rafael C. Guadagnin y Teodoro S. Kaufman. Synthesis 1233-1242 (2011). Synthesis 2011 1233.pdf (182707)
 
Isolation, Synthesis and Complement Inhibiting Activity of the Naturally Occurring K-76, its Analogues and Derivatives. Enrique L. Larghi y Teodoro S. Kaufman. Arkivoc vii, 49-102 (2011). Número homenaje ‘Química Orgánica en Argentina’. Arkivoc 2011 vii 49.pdf (526166)
 
Experimentally Designed, Validated HPLC Simultaneous Determination of Pridinol and Diclofenac in their Combined Pharmaceutical Formulations, which Allows Limiting Diclofenac Related Compound A. Silvana E. Vignaduzzo, Patricia M. Castellano y Teodoro S. Kaufman. J. Liq. Chromatogr. Relat. Technol. 33, 1720-1732 (2010). J Liq Chromatogr Relat Technol 2010 33 1720.pdf (979297)
 
Synthesis of 2-Diphenylphosphinoyl-3,5-diaryl-3,4-dihydro-2H-telluropyrans by Reaction of Chalcones  with 
bis[(Diphenylphosphinoyl)methyl]telluride. Claudio C. Silveira, Francieli Rinaldi, Mariana M. Bassaco y Teodoro S. Kaufman. Tetrahedron Lett. 51, 4563-4565 (2010). Tetrahedron Lett 2010 51 4563.pdf (230831)
 
Chiral Auxiliary-Mediated Enantioenrichment of (±)-Ibuprofen, under Steglich Conditions, with Secondary Alcohols Derived from (R)-Carvone. Marcela Amongero y Teodoro S. Kaufman. J. Braz. Chem. Soc. 21, 1017-1036 (2010). J Braz Chem Soc 2010 21 1017.pdf (448348)
 
Development and Validation of a Dissolution Test for Meloxicam and Pridinol Mesylate in their Combined Tablet Formulation. Silvana E. Vignaduzzo, Patricia M. Castellano y Teodoro S. Kaufman. Indian J. Pharm Sci. 72, 197-203 (2010). Indian J Pharm Sci 2010 72 197.pdf (2726490)
 
A Novel Chemometric Strategy for the Estimation of Extra Virgin Olive Oil Adulteration with Edible Oils. Rubén M. Maggio, Lorenzo Cerretani, Emma Chiavaro, Teodoro S. Kaufman y Alessandra Bendini. Food Control 21, 890-895 (2010). Food Control 2010 21 890.pdf (1726669)